Senior Assistant Professor Shioi Faculty of Fukuoka Medical Technology won the JB Paper Award at the 98th Annual Meeting of the Japanese Biochemical Society (100th Anniversary of the Society's Founding)Fukuoka Campus

At the 98th Annual Meeting of the Japanese Biochemical Society (commemorating the 100th anniversary of its founding), held at the Kyoto International Conference Center (Kyoto City, Kyoto Prefecture) from November 3rd (Monday, national holiday) to November 5th, 2025, Senior Assistant Professor Shioi Narumi, Faculty of Fukuoka Medical Technology Department of Medical Technology, Fukuoka, Teikyo University, won the JB (The Journal of Biochemistry) Best Paper Award for his paper "Structure-specific DNA endonuclease T7 endonuclease I cleaves DNA containing UV-induced DNA lesions." The award ceremony was held on the 4th (Tuesday) of the same month.

This paper reveals a new substrate specificity for an enzyme called T7 endonuclease I, which recognizes and cleaves DNA damage caused by ultraviolet light. Previously, it was thought that this enzyme mainly recognized and cleaved hairpin structures and mismatches, which are structural abnormalities in DNA. However, this research has shown that it also specifically recognizes and cleaves UV-damaged DNA. This discovery is expected to lead to new methods for investigating DNA damage caused by sunlight and UV light, as well as to an understanding of the mechanisms by which cells repair damage.
This result not only deepens our understanding of DNA repair mechanisms, but also demonstrates its potential application in UV damage detection and gene manipulation, which was highly praised and led to the award of the JB Best Paper Award.

We look forward to seeing even greater success from Senior Assistant Professor Shioi in the future.

For more information about the 98th Annual Meeting of the Japanese Biochemical Society (100th Anniversary of the Society's Founding), please click here.
For more information about Senior Assistant Professor Shioi Narumi, click here

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